Horehound herb, derived from the plant Marrubium vulgare, can be prepared and utilized in various forms. To start, the plant itself is typically grown in full sun and well-drained soils, often in poor or neglected areas where it thrives. It can be planted from seed, cuttings, or division, with seeds sown shallowly about three weeks before the last expected frost date. Once the plant is established, the leaves and stems can be harvested, particularly after the plant flowers[1][2].
For medicinal and culinary uses, the leaves and stems of the horehound plant are often dried. To make horehound tea, for example, approximately 1/4 to 1/2 teaspoon of the dried root or leaves is boiled in about 7 ounces of water for ten minutes[3]. For candies and cough drops, dried horehound is steeped in boiling water to create an infusion, which is then strained and mixed with sugar and other ingredients. This mixture is then boiled to the hard crack stage (around 300°F) to create the candy, which can be molded into various shapes and stored in an airtight container[4][5].
The safety profile of horehound herb for human consumption is generally considered favorable when used in moderate amounts, particularly in food and beverages. Horehound has been granted generally recognized as safe (GRAS) status by the US Food and Drug Administration (FDA) as a flavoring agent and essential oil[1][2][3]. When consumed in food amounts, it is likely safe for most people. However, when taken as a medicine, it is possibly safe, but large amounts can be potentially unsafe and may cause adverse effects such as vomiting, nausea, dry mouth, and cardiac irregularities in higher doses[1][2][3]. It is contraindicated during pregnancy due to its emmenagogue and abortifacient effects[1][2][3].
While the herb itself is not typically associated with heavy metal contamination or heavy pesticide use, there are other considerations to be aware of. Horehound can grow in poor soil conditions and may colonize eroded areas, which could potentially expose it to environmental contaminants. However, there is no specific evidence to suggest that horehound is more prone to heavy metal contamination than other plants. Regarding pesticide use, since horehound is often found in wild or uncultivated areas, the risk of pesticide contamination is likely lower compared to cultivated crops. Pathogen risks are also not well-documented, but as with any plant material, proper handling, drying, and storage are crucial to prevent contamination. Additionally, the plant's bitter alkaloid content, particularly marrubin, makes it unpalatable to grazing animals, which might reduce the likelihood of pathogen transmission through animal contact[4].
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